Jan Franse, ancestor of all the Van Hoesens in America, was an early resident of Fort Orange, now Albany, New York, and died at Claverack, 1667. He came to America from a town in Holland, near the Zuyder Zee, called Huesen. He acted as commissioner for the West India Company, was interested in shipping, purchased several lots and erected buildings in Albany. June 5, 1662, he bought from the Indians for five hundred guilders in beavers, at Claverack, several hundred acres of land along the river including the site of the present city of Hudson. He was an early member of the Dutch Reformed church at Albany. He married Volkie Jurianse, who survived him and married, (second) Gerrit Visbeck, master of a vessel. Children:
- Jurian;
- Volkert;
- Anna, married Luyka Berritsen;
- Styntje, married Jan Tys Gons;
- Maria, married Hendrick Coenratse;
- Catherina, married Frank Hardurgh;
- Johanna;
- Jacob Janse, see forward.
Jacob Janse and Volkert in 1689 were farmers and belonged to Captain Gerrit Tunisen's company. Volkert was ensign in 1700.
(II) Jacob Janse, son of Jan Franse and Volkie (Jurianse) Van Hoesen, was of Claverack, Columbia county, New York, 1720. He probably built the old Van Hoesen House, about 1700. He married Judik Franse Clauw. Children:
- Jan,
- Elsje, baptized February 12, 1696;
- Maria, Jacob.
(III) Jan, son of Jacob Janse and Judik Franse (Clauw) Van Hoesen, was the first of his name to make settlement in Greene county, New York. He was of Coxsackie as early as 1710, and is the founder of that branch of the family. He owned considerable land in Greene county which he cleared in part and cultivated. He married Rachel, daughter of Jan Casparse and Rachel Holenbeck. Children:
- Jan Casparse, see forward;
- Judith, born at Coxsackie and baptized at Klinkenburgh, November 11, 1716;
- Caspar, born April 6, at Coxsackie, baptized February 26, 1721.
(IV) Jan Casparse, son of Jan and Rachel (Holenbeck) Van Hoesen, was born "last fall" at Coxsackie and baptized at the same place, December 10, 1710. He married and had issue.
(V) Garrett, son of Jan Casparse Van Hoesen, was born about 1740, married and had issue.
(VI) John Casparse, son of Garrett Van Hoesen, was born 1772. He was a resident of Athens, Greene county, New York. He married Elizabeth Clow and had issue.
(VII) Jacob, son of John Casparse and Elizabeth (Clow) Van Hoesen, was born in Athens, Greene county, New York, about 1800. He married Hannah Witbeck, daughter of the Witbeck family who early settled at the foot of the Catskills in Greene county.
(VIII) Dr. Isaac J. Van Hoesen, son of Jacob and Hannah (Witbeck) Van Hoesen, was born in the town of Athens, New York, died 1901, aged sixty-three years. He was educated in the town schools and early began to prepare for the profession of medicine. He was a graduate of Long Island College and Hospital, and ranked very high in his profession.
He settled in the village of Medway, Greene county, where he practiced until his death. He was well known among his professional brethren and highly-esteemed. He was an authority on many medical points and lectured before the students of Albany Medical College on special subjects. He was beloved among his patients and held a place in their hearts and homes that only the country physician of long standing ever occupies. He served a term as coroner of Greene county and was connected with the Free and Accepted Masons of Greenville. His professional societies were the Greene County and the New York State Medical. Politically he was a Democrat, and in religious faith a member of the Dutch Reformed church. He married (first) Mary Green, who bore a daughter,
- Minnie L., married Clinton Wheeler, of Coxsackie.
He married (second) Abbie L. King, born March 24, 1853, daughter of Levi and Melissa (Lampman) King. Children:
- Frederick G., born August 31, 1878, married Agnes Smith, of Catskill; children:
- Gertrude, aged four years, and
- Ernest, aged two years.
- Isaac E., see forward.
(IX) Isaac E., son of Dr. Isaac J. and Abbie L. (King) Van Hoesen, was born September 2, 1882. He was educated in the public schools of Medway and Coxsackie high school. He decided upon his father's profession, medicine, and studied under his preceptorship. He then entered Albany Medical College (Union University), from which he was graduated M.D., 1903. He spent one year as interne [sic] at Albany City Hospital and then established himself in Coxsackie in the general practice of his profession. He is a capable physician and commands a satisfactory practice. He married, September 25, 1906, Maria A. Gauger, of Albany, New York. Child:
- Willis MacDonald, born June 19, 1908.